Everything from Yesterday. Through Natural Conversation.
Natural Language Replaces Manual Clicking
Yesterday we showed you AIVA's powerful manual interface: customized analysis panel, ACMG classification, protein visualization, and comprehensive analysis features.
Today? AI does it all through conversation.
The same features, the same power: filtering, flagging, classification, annotation. Just ask instead of click.
Explore variants with natural language
Real Query Examples
Here's what AI-powered variant analysis looks like in practice:
Complex Variant Filtering
"Count ClinVar reported pathogenic (no conflicts) variants by zygosity in each of the samples in @multi_sample_vcf"
AIVA: Identifies multiple samples → Filters by pathogenicity and zygosity → Returns with a table of variant counts
ACMG Re-classification
"Reclassify BRAF:c.2213T>G for rasopathy phenotype using ACMG criteria. list all applied codes and final classification with citations"
AIVA: Annotates variant → Reviews Literature for phenotype association → Queries AIVA-KG → Evaluates ACMG evidence criteria → Calculates score → Assigns classification → Documents evidence
Flagging & Comments
"Flag and add a comment to variant rs123456 in @sample101: high CADD score, associated with phenotype, rare in gnomAD4.1, high confidence"
AIVA: Locates variant by rs ID → Flags variant → Adds threaded comment → Timestamps and attributes to user
Re-classifying a VUS (BRAF:c.2213T>G) using ACMG criteria
Real-Time Transparency
Watch the AI work in real-time. See which databases are queried, which filters are applied, and which variants are flagged. Every action is transparent and you maintain complete control.
Your Choice. Same Platform.
AIVA doesn't force you to choose between manual control and AI automation. Use both, depending on your needs.
Experience AI-Powered Analysis
See how natural language transforms variant analysis.